Center for Personalized Therapeutics

The university of chicago

Center for Personalized Therapeutics

By making pharmacogenomic information prompt, accessible, and understandable for physicians, The Center for Personalized Therapeutics (CPT) leads the way in translating genomic discovery to improved care for patients.

Explore our program

In 2000 the first draft sequence of the human genome was released, and widespread use of techniques to implement and translate such genomic knowledge was slow to be adopted by the medical community.  In 2009, the future leadership of the CPT felt that there was a critical mass of information regarding the association of individual genetic variability with drug-related adverse event and response outcomes and therefore established the Center.

The Center embarked on its first project in 2011, the 1200 Patients Project, which uses a preemptive ‘medical system model’ for personalized care that makes relevant pharmacogenomic information instantaneously accessible at the time of prescribing to reduce the use of inapprorpiate and high risk medications in patients for whom pharmacogenomic results are known, thereby decreasing adverse events and non-responsive rates.

Research

This section includes all of the articles and paper

Projects

This includes the 4 projects (The 1200 Patients Projects, The ACCOuNT Project, Impress Trial, PhOCus Trial, GPS project)

Training & Career

This includes: fellowship training, career opportunity, undergrad opportunity, Benjamin McAllister, Pfizer

Collaboration

 

Collaboration with other institutions. CLIA lab. 

“Translating Genomic Discovery to Therapeutics”

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Leader in personal Therapeutics

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Established Projects

Patients involved

Clincal Trials

PUblished paper

OUr Goal

One of the key goals of the Center is to develop systems for efficient collection, storage and clinical application of genetic data and to train physicians in the use of personalized genetic information as tools in patient care which can help identify the patients most likely to respond to, or be harmed by, specific therapies.

Current CPT reserach focuses on the evaluation of pharmacogenomics markers in the context of clinical trials at all phases of drug development.  In addition, researchers are working in the area of new drug development by using genomic research findings to identify new targets, leading to the development of antibodies, peptide vaccines, and small molecular compounds.

In the near future, the Center plans to expand the availability of pre-emptive clinical testing for use in additional patient populations at a variety of institutions around the counry. The ultimate goal of the Center is to develop innovative, personalized and effective therapies for all patients.

Our Latest Projects

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Exceptional Training & Career opportunities

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For Graduate Fellows

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For Post Doctoral Fellows

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Career Opportunities

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  • Graduate student – 90%
  • Post Graduate student – 77%
  • Other – 25%
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From Our Faculty & Trainees

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Peter H. O'Donnell, MD

Deputy Director, Center for Personalized Therapeutics, The University of Chicago

“There are many variations of passages of Lorem Ipsum available, but the majority have suffered alteration by injected humour.”

Mark J. Ratain, MD

Professor of Medicine, Director, Center for Personalized Therapeutics | Associate Director for Clinical Sciences, Comprehensive Cancer Center, The University of Chicago

“There are many variations of passages of Lorem Ipsum available, but the majority have suffered alteration by injected humour.”

Thomas Chen, MD, PharmD

Assistant Professor of Medicine, Section of Hospital Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago | Hospitalist Champion, Center for Personalized Therapeutics

“There are many variations of passages of Lorem Ipsum available, but the majority have suffered alteration by injected humour.”

Tom Ewer

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