Center for Personalized Therapeutics

The university of chicago

Center for Personalized Therapeutics

By making pharmacogenomic information prompt, accessible, and understandable for physicians, The Center for Personalized Therapeutics (CPT) leads the way in translating genomic discovery to improve care for patients.

Explore our program

In 2000 the first draft sequence of the human genome was released, and widespread use of techniques to implement and translate such genomic knowledge was slow to be adopted by the medical community.ย  In 2009, the future leadership of the CPT felt that there was a critical mass of information regarding the association of individual genetic variability with drug-related adverse event and response outcomes and therefore established the Center.

The Center embarked on its first project in 2011, theย 1200 Patients Project, which uses a preemptive medical system model that reduces the use of high risk medications. Later, the CPT established the ACCOuNT Project, the Impress Trial, the PhOCus Trial, and the PROTECT-Rx trial.

Research

CPT leads exceptional research on translational genomic discoveries and pharmocogenomics.ย 

Projects

CPT conducts clinical trials in diverse medical fields, including perioperative, oncology, in-patient, out-patient, and beyond.

Training & Career

CPT offers opportunities for undergraduate, graduate, and post-doctoral trainees.ย 

Collaboration

CPT partners with other departments and specialties to advance our understanding of the human genome.

Translating Genomic Discovery to Therapeutics

A word from the deputy director of Center for Personalized Therapeutics. Dr. O’Donnell talks about the program and how it is leading the field of clinical pharmacogenomics research and implementation.

๐Ÿ“ŒNext time in Zoom meeting we can plan to record Dr. O’Donnell’s landing video.ย 

 

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Our faculty

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Leader in personalized Therapeutics

We are the leading center of personalized therapeutics in the US. Aiming to lead the way in translating genomic discovery to improved care for patients, our center have 3ย completed and four ongoing projects. With 529 providers enrolled in our studies, CPT strives to ______. ย {Better wording for this needed @ Emily} ๐Ÿ“Œ

Total providers enrolled in the US

Past and Ongoing Projects

Providers enrolled in ACCOuNT Project

Providers enrolled in ImPreSS Trial

OUr Goal

One of the key goals of the Center is to develop systems for efficient collection, storage, and clinical application of genetic data and to train physicians in the use of personalized genetic information as tools in patient care. We hope this can help identify the patients most likely to respond to, or be harmed by, specific therapies.

 

Current CPT research focuses on the evaluation and application of pharmacogenomicsย  information in the context of clinical trials at all phases of drug development.

 

In the near future, the Center plans to expand the availability of pre-emptive clinical testing for use in additional patient populations at a variety of institutions around the country.ย ย Theย ultimate goal of the Center is to develop innovative, personalized and effective therapies for all patients, and promote the use of genetic testing to develop personalized treatment plans.ย 

Our Latest Projects

The Center of Personalized Therapeutics has completed three projects, including the 1200 Patients Project, ACCoUNT Project, ImPreSS Trial and PhOCus Trial. CPT is working on Chablis Project, PTC Project, Diversity Studies, and Pharmacoeconomics.ย 

Completed Projects

The 1200 Patients Project

Piloting the use of pharmacogenomics in routine medical care.

ImpreSS Trial

Implementing pharmacogenomic testing in anesthesia and perioperative medicine.

The ACCOuNT Project

Examining pharmacogenomic implementation in the context of minority health disparities

PhOCus Trial

Studying pharmacogenomic testing in Oncology care

Exceptional Training & Career opportunities

CPT offers training and career opportunities for a diverse array of education backgrounds. If you are interested in ______ (what CPT offers) _______, do )_______ (Call for action, maybe apply?). ๐Ÿ“Œ

๐Ÿ“Œ Text for different career pathwayย 

๐Ÿ“Œ Statistics for the trainees

  • Graduate student – 90%
  • Post Graduate student – 77%
  • Other – 25%

For Graduate Fellows

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For Post Doctoral Fellows

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Career Opportunities

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From Our Faculty & Trainees

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Dr. Peter O'Donnell, MD

Deputy Director, Center for Personalized Therapeutics, The University of Chicago

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Mark J. Ratain, MD

Professor of Medicine, Director, Center for Personalized Therapeutics | Associate Director for Clinical Sciences, Comprehensive Cancer Center, The University of Chicago

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Thomas Chen, MD, PharmD

Assistant Professor of Medicine, Section of Hospital Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago | Hospitalist Champion, Center for Personalized Therapeutics

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Tom Ewer

Blogger, Elegant Themes