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RESEARCH UPDATES

Check here for our most recent research articles, talks, and presentations. Please use the left navigation for other updates, including previous awards and headlines. 


PEER-REVIEWED RESEARCH ARTICLES

Members of the Center for Personalized Therapeutics and the Center for Research Informatics describe the architecture and design of our Genomic Prescribing System (GPS). Specifically, the article discusses the transformation of patient-specific genomic data into clinical decision support summaries for healthcare providers, the end-to-end architecture of GPS, and utilization metrics since implementation. View the article here


Dr. O'Donnell and members of the Center for Personalized Therapeutics studied medication changes made by providers who had access to patient-specific pharmacogenomic results and clinical decision support through the 1200 Patients Project. View the article here


Former Center for Personalized Therapeutics fellow, Dr. Yee Ming Lee, along with Pritzker School of Medicine student Ryan McKillip and other CPT members, conducted patient focus groups and compared patient perceptions of genomic testing. View the article here


Drs. Ratain and O'Donnell, along with other members of the Pharmacogenomics Research Network (PGRN), describe outcomes and metrics of various pharmacogenomic implementation programs. View the article here


Pritzker School of Medicine student Ryan McKillip, along with other members of the Center for Personalized Therapeutics, studied patient survey responses after clinic visits at which preemptive PGx results were available to providers. This article was published in Clinical Pharmacology and Therapeutics. View the article here


Dr. O'Donnell, Dr. Ratain, and our programmer, Keith Danahey describe why pharmacogenomics could impact all of us. View the article here, which was published in Clinical Pharmacology and Therapeutics in April 2016. 


Members of the Center for Personalized Therapeutics develop and describe a novel disease-drug association tool that enables pharmacogenomic-based prescribing. View the article here


Members of the Center for Personalized Therapeutics analyze the use of pharmacogenomics in Cardiology in this 2015 article published in Mayo Clinic proceedings. View the article here


 Preliminary data from The 1200 Patients Project published in the American Journal of Medical GeneticsView the article here


RECENT TALKS AND PRESENTATIONS

A number of CPT members presented abstracts at ASCPT 2018. These presentors included Annabel Boeke, Pritzker School of Medicine student mentored by Dr. O'Donnell, Brittany Borden, CPT Clinical Research Coordinator, and Ellie Jhun, PharmD, PhD, postdoctoral fellow mentored by Dr. O'Donnell. Meeting abstracts are available here.


Dr. Peter O'Donnell was a featured speaker at the 2018 University of Florida Precision Medicine Conference. His talk focused on the effectiveness of drug prescribing based on pharmacogenomics. 


Dr. Peter O'Donnell was the keyote speaker at the Joint Luncheon of the Molecular Pathology and Personalized Medicine Divisions at the American Association for Clinical Chemistry annual meeting. His talk was titled "Bringing Genomics to the Point-of-Care to Support Prescribing in the Era of Precision Medicine". 


Dr. Peter O'Donnell gave a riveting talk to the University of Chicago greater community titled "Doctor, Did You Check My DNA Before Prescribing That?" as part of the Harper Lecture series.


Dr. Peter O'Donnell gave a presentation titled "A Genomic Prescribing System (GPS) for Clinical Implementation of Germline Pharmacogenomics (PGx)" at the 74th Annual Meeting of the Japanese Cancer Society. The talk focused on the use of pharmacogenomics in Oncology.


Center for Personalized Therapeutics programmer Keith Danahey presented an abstract at the AMIA 2015 Joint Summits on Translational Science focusing on the implementation of the Genomic Prescribing System. Co-authors include Dr. Samuel Volchenbaum, Dr. Mark Ratain, and Dr. Peter O'Donnell. 


Dr. Peter O'Donnell's presentation in February at The University of Florida College of Pharmacy Department of Pharmacotherapy and Translational Research Seminar Series. Watch the video here